Will these interfere with jack points?

No. The side skirts are designed to clear factory jack point access on both sides. Your floor jack will slip underneath without obstruction.

Do these affect ground clearance?

Minimally. The Bomber profile extends down slightly from the body line but doesn't add height or drop the suspension contact point. Low-speed scraping on severe dips is possible depending on your setup.

How vulnerable are they to road debris?

FRP is durable but not impact-proof. Low-speed bumps and scrapes will show damage more readily than steel. Highway driving is fine; aggressive off-road or unpaved surfaces increase damage risk.